PDBe 2d8u

Solution NMR

Solution structure of the B-box domain of the human tripartite motif-containing 63 protein

Released:
Source organism: Homo sapiens
Entry authors: Miyamoto K, Kigawa T, Tomizawa T, Koshiba S, Inoue M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 ubiquitin-protein ligase TRIM63 Chain: A
Molecule details ›
Chain: A
Length: 64 amino acids
Theoretical weight: 6.78 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q969Q1 (Residues: 119-169; Coverage: 14%)
Gene names: IRF, MURF1, RNF28, SMRZ, TRIM63
Structure domains: Herpes Virus-1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 95%
Refinement method: torsion angle dynamics
Chemical shifts: BMR11327  
Expression system: Not provided