› 2d3v

X-ray diffraction
1.85Å resolution

Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11)

Released:
DOI: 10.2210/pdb2d3v/pdb
PDB entry 2d3v coloured by chain, front view.
PDB entry 2d3v coloured by chain, side view.
PDB entry 2d3v coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the human monocyte-activating receptor, "Group 2" leukocyte Ig-like receptor A5 (LILRA5/LIR9/ILT11).
Shiroishi M, Kajikawa M, Kuroki K, Ose T, Kohda D, Maenaka K
J Biol Chem 281 19536-44 (2006)
PMID: 16675463

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukocyte immunoglobulin-like receptor subfamily A member 5 Chain: A
Molecule details ›
Chain: A
Length: 196 amino acids
Theoretical weight: 22.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A6NI73 (Residues: 42-237; Coverage: 76%)
Gene names: ILT11, LILRA5, LILRB7, LIR9
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 2 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 28.08Å b: 58.645Å c: 131.619Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.234 0.269
Expression system: Escherichia coli BL21(DE3)

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Citations

11 review citations

Signaling and ligand interaction of ILT7: receptor-mediated regulatory mechanisms for plasmacytoid dendritic cells.
Cao et al. (2010)
10 more

6 mentions without citation

Structure of the three N-terminal immunoglobulin domains of the highly immunogenic outer capsid protein from a T4-like bacteriophage.
Fokine et al. (2011)
5 more