› 2cwm

X-ray diffraction
1.95Å resolution

Native Crystal Structure of NO releasing inductive lectin from seeds of the Canavalia maritima (ConM)

Released:
DOI: 10.2210/pdb2cwm/pdb
PDB 2cwm coloured by chain and viewed from the front.
PDB 2cwm coloured by chain and viewed from the side.
PDB 2cwm coloured by chain and viewed from the top.
Source organism: Canavalia rosea
Primary publication:
Native crystal structure of a nitric oxide-releasing lectin from the seeds of Canavalia maritima.
Gadelha CA, Moreno FB, Santi-Gadelha T, Cajazeiras JB, Rocha BA, Assreuy AM, Lima Mota MR, Pinto NV, Passos Meireles AV, Borges JC, Freitas BT, Canduri F, Souza EP, Delatorre P, Criddle DN, de Azevedo WF, Cavada BS
J. Struct. Biol. 152 185-94 (2005)
PMID: 16337811

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Concanavalin-Ma Chains: A, D
Molecule details ›
Chains: A, D
Length: 237 amino acids
Theoretical weight: 25.49 KDa
Source organism: Canavalia rosea
UniProt:
  • Canonical: P81364 (Residues: 1-35, 36-236; Coverage: 100%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand MN 2 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P21212
Unit cell:
a: 67.916Å b: 97.617Å c: 71.021Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.189 0.237

Quick links

Citations

1 review citation

ConA-Like Lectins: High Similarity Proteins as Models to Study Structure/Biological Activities Relationships.
Cavada et al. (2018)
23 other articles

1 mention without citation

Effect of lectins from Diocleinae subtribe against oral Streptococci.
Cavalcante et al. (2011)