2ct0

Solution NMR

Solution structure of the RING domain of the Non-SMC element 1 protein

Released:
Source organism: Homo sapiens
Entry authors: Miyamoto K, Sato M, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural maintenance of chromosomes element 1 homolog Chain: A
Molecule details ›
Chain: A
Length: 74 amino acids
Theoretical weight: 8.05 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q8WV22 (Residues: 181-241; Coverage: 23%)
Gene names: HSPC333, HSPC337, NSMCE1
Sequence domains: RING-like domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: torsion angle dynamics
Chemical shifts: BMR11315  
Expression system: Not provided