PDBe 2coe

Solution NMR

Solution structure of BRCT domain of terminal deoxynucleotidyltransferase

Released:
Source organism: Homo sapiens
Entry authors: Nagashima T, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA nucleotidylexotransferase Chain: A
Molecule details ›
Chain: A
Length: 120 amino acids
Theoretical weight: 12.9 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P04053 (Residues: 19-125; Coverage: 21%)
Gene names: DNTT, TDT
Sequence domains: BRCA1 C Terminus (BRCT) domain
Structure domains: BRCT domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided