Solution NMR

Solution structures of the HTH domain of human LCoR protein

Source organism: Homo sapiens
Entry authors: Nameki N, Umehara T, Sato M, Koshiba S, Inoue M, Tanaka A, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Ligand-dependent corepressor Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 7.82 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q96JN0 (Residues: 343-405; Coverage: 15%)
Gene names: C10orf12, KIAA1795, LCOR, MLR2
Sequence domains: helix-turn-helix, Psq domain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrained molecular dynamics
Expression system: Not provided