› › Function and Biology

Solution structures of the LIM domain of human NEDD9 interacting protein with calponin homology and LIM domains

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

Quick links

EC 1.6.3.1: NAD(P)H oxidase (H(2)O(2)-forming)

Reaction catalysed:
NAD(P)H + O(2) = NAD(P)(+) + H(2)O(2)
Systematic name:
NAD(P)H:oxygen oxidoreductase (H(2)O(2)-forming)
Alternative Name(s):
  • Dual oxidase
  • NAD(P)H oxidase
  • NAD(P)H:oxygen oxidoreductase
  • NADPH oxidase
  • P138tox
  • THOX2
  • ThOX
  • Thyroid NADPH oxidase
  • Thyroid oxidase
  • Thyroid oxidase 2

EC 1.14.13.225: F-actin monooxygenase

Reaction catalysed:
[F-actin]-L-methionine + NADPH + O(2) + H(+) = [F-actin]-L-methionine-(R)-S-oxide + NADP(+) + H(2)O
Systematic name:
[F-actin]-L-methionine,NADPH:O(2) S-oxidoreductase
Alternative Name(s):
  • MICAL (gene name)

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00412
Domain description: LIM domain
Occurring in:
  1. [F-actin]-monooxygenase MICAL1
The deposited structure of PDB entry 2co8 contains 1 copy of Pfam domain PF00412 (LIM domain) in [F-actin]-monooxygenase MICAL1. Showing 1 copy in chain A.

InterPro InterPro annotation
IPR001781
Domain description: Zinc finger, LIM-type
Occurring in:
  1. [F-actin]-monooxygenase MICAL1

Structure domain

CATH CATH domain
2.10.110.10
Class: Mainly Beta
Architecture: Ribbon
Topology: Cysteine Rich Protein
Homology: Cysteine Rich Protein
Occurring in:
  1. [F-actin]-monooxygenase MICAL1
The deposited structure of PDB entry 2co8 contains 1 copy of CATH domain 2.10.110.10 (Cysteine Rich Protein) in [F-actin]-monooxygenase MICAL1. Showing 1 copy in chain A.
SCOP SCOP annotation
57736
Class: Small proteins
Fold: Glucocorticoid receptor-like (DNA-binding domain)
Superfamily: Glucocorticoid receptor-like (DNA-binding domain)
Occurring in:
  1. [F-actin]-monooxygenase MICAL1
The deposited structure of PDB entry 2co8 contains 2 copies of SCOP domain 57736 (LIM domain) in [F-actin]-monooxygenase MICAL1. Showing 2 copies in chain A.

Quick links