› 2co8

Solution NMR

Solution structures of the LIM domain of human NEDD9 interacting protein with calponin homology and LIM domains

Released:
DOI: 10.2210/pdb2co8/pdb
PDB entry 2co8 coloured by chain, ensemble of 20 models, front view.
PDB entry 2co8 coloured by chain, ensemble of 20 models, side view.
PDB entry 2co8 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Sato M, Tomizawa T, Saito K, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reactions catalysed: 
[F-actin]-L-methionine + NADPH + O(2) + H(+) = [F-actin]-L-methionine-(R)-S-oxide + NADP(+) + H(2)O
NAD(P)H + O(2) = NAD(P)(+) + H(2)O(2)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186227 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
[F-actin]-monooxygenase MICAL1 Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 8.84 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q8TDZ2 (Residues: 687-755; Coverage: 7%)
Gene names: MICAL, MICAL1, NICAL
Sequence domains: LIM domain
Structure domains: Cysteine Rich Protein

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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