Solution NMR

Solution structures of the LIM domain of human NEDD9 interacting protein with calponin homology and LIM domains

Source organism: Homo sapiens
Entry authors: Sato M, Tomizawa T, Saito K, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
[F-actin]-L-methionine + NADPH + O(2) + H(+) = [F-actin]-L-methionine-(R)-S-oxide + NADP(+) + H(2)O
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
[F-actin]-monooxygenase MICAL1 Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 8.84 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q8TDZ2 (Residues: 687-755; Coverage: 7%)
Gene names: MICAL, MICAL1, NICAL
Sequence domains: LIM domain
Structure domains: Cysteine Rich Protein

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Chemical shifts: BMR10247  
Expression system: Not provided