2cmy

X-ray diffraction
2.25Å resolution

Crystal complex between bovine trypsin and Veronica hederifolia trypsin inhibitor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cationic trypsin Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Trypsin inhibitor Chain: B
Molecule details ›
Chain: B
Length: 34 amino acids
Theoretical weight: 4.06 KDa
Source organism: Veronica hederifolia
UniProt:
  • Canonical: P85981 (Residues: 1-34; Coverage: 100%)

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.1
Spacegroup: P212121
Unit cell:
a: 60.657Å b: 63.928Å c: 71.698Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.253