2cl3

X-ray diffraction
1.9Å resolution

Crystal structure of human Cleavage and Polyadenylation Specificity Factor 5 (CPSF5)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cleavage and polyadenylation specificity factor subunit 5 Chain: A
Molecule details ›
Chain: A
Length: 230 amino acids
Theoretical weight: 26.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O43809 (Residues: 19-227; Coverage: 92%)
Gene names: CFIM25, CPSF25, CPSF5, NUDT21
Sequence domains: Nucleotide hydrolase
Structure domains: Nucleoside Triphosphate Pyrophosphohydrolase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P3121
Unit cell:
a: 79.92Å b: 79.92Å c: 72.22Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.171 0.17 0.207
Expression system: Escherichia coli BL21(DE3)