Assemblies
Assembly Name:
Caspase-3 complex and peptide
Multimeric state:
hetero hexamer
Accessible surface area:
18238.71 Å2
Buried surface area:
15335.58 Å2
Dissociation area:
1,060.19
Å2
Dissociation energy (ΔGdiss):
7.44
kcal/mol
Dissociation entropy (TΔSdiss):
10.82
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-154734
Macromolecules
Chain: A
Length: 147 amino acids
Theoretical weight: 16.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Caspase domain
InterPro:
Length: 147 amino acids
Theoretical weight: 16.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P42574 (Residues: 29-175; Coverage: 53%)
Pfam: Caspase domain
InterPro:
- Peptidase C14 family
- Caspase-like domain superfamily
- Peptidase C14A, caspase catalytic domain
- Peptidase C14, p20 domain
- Peptidase C14, caspase domain
- Peptidase family C14A, His active site
- Peptidase family C14A, cysteine active site
Chain: B
Length: 103 amino acids
Theoretical weight: 11.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Caspase domain
InterPro:
Length: 103 amino acids
Theoretical weight: 11.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P42574 (Residues: 176-277; Coverage: 37%)
Pfam: Caspase domain
InterPro:
- Caspase-like domain superfamily
- Peptidase C14A, caspase catalytic domain
- Peptidase C14, caspase domain
- Peptidase C14, caspase non-catalytic subunit p10
Chain: I
Length: 6 amino acids
Theoretical weight: 661 Da
Source organism: synthetic construct
Expression system: Not provided
Length: 6 amino acids
Theoretical weight: 661 Da
Source organism: synthetic construct
Expression system: Not provided
