2c9t

X-ray diffraction
2.25Å resolution

Crystal Structure Of Acetylcholine Binding Protein (AChBP) From Aplysia Californica In Complex With alpha-Conotoxin ImI

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octadecamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Neur_chan_LBD domain-containing protein Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 217 amino acids
Theoretical weight: 24.69 KDa
Source organism: Aplysia californica
UniProt:
  • Canonical: Q8WSF8 (Residues: 20-236; Coverage: 100%)
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain
Alpha-conotoxin ImI Chains: K, M, O, P, Q, R, S, T
Molecule details ›
Chains: K, M, O, P, Q, R, S, T
Length: 13 amino acids
Theoretical weight: 1.36 KDa
Source organism: Conus imperialis
UniProt:
  • Canonical: P50983 (Residues: 5-16; Coverage: 71%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21
Unit cell:
a: 113.211Å b: 123.131Å c: 118.749Å
α: 90° β: 117.47° γ: 90°
R-values:
R R work R free
0.171 0.168 0.227