Structure analysis

insuline(60sec) and UV laser excited fluorescence

X-ray diffraction
1.5Å resolution
Source organism: Homo sapiens
Assembly composition:
Non-polymer only tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: Non-polymer only tetramer
Accessible surface area: 5300 Å2
Buried surface area: 4000 Å2
Dissociation area: 550 Å2
Dissociation energy (ΔGdiss): 1 kcal/mol
Dissociation entropy (TΔSdiss): 9 kcal/mol
Interface energy (ΔGint): -37 kcal/mol
Symmetry number: 2

Macromolecules

Chain: A
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01308 (Residues: 90-110; Coverage: 24%)
Gene name: INS
InterPro:

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Chain: B
Length: 29 amino acids
Theoretical weight: 3.33 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01308 (Residues: 25-53; Coverage: 34%)
Gene name: INS
InterPro:

Search similar proteins