X-ray diffraction
2.1Å resolution

Human Rabex-5 residues 1-74 in complex with Ubiquitin


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rab5 GDP/GTP exchange factor Chains: A, C, E, G, I, K
Molecule details ›
Chains: A, C, E, G, I, K
Length: 74 amino acids
Theoretical weight: 8.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9UJ41 (Residues: 1-74; Coverage: 15%)
Gene names: RABEX5, RABGEF1
Sequence domains: A20-like zinc finger
Ubiquitin Chains: B, D, F, H, J, L
Molecule details ›
Chains: B, D, F, H, J, L
Length: 76 amino acids
Theoretical weight: 8.58 KDa
Source organism: Bos taurus
Expression system: Not provided
  • Canonical: P0CH28 (Residues: 609-684; Coverage: 11%)
Gene name: UBC
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P1
Unit cell:
a: 44.3Å b: 68.9Å c: 98.5Å
α: 108.2° β: 102.7° γ: 90.4°
R R work R free
0.198 0.195 0.238
Expression systems:
  • Escherichia coli
  • Not provided