PDBe 2c4f

X-ray diffraction
1.72Å resolution

crystal structure of factor VII.stf complexed with pd0297121

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Factor VII heavy chain Chain: H
Molecule details ›
Chain: H
Length: 254 amino acids
Theoretical weight: 28.1 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P08709 (Residues: 213-466; Coverage: 57%)
Gene name: F7
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Factor VII light chain Chain: L
Molecule details ›
Chain: L
Length: 142 amino acids
Theoretical weight: 16.36 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P08709 (Residues: 61-202; Coverage: 32%)
Gene name: F7
Sequence domains:
Tissue factor Chain: T
Molecule details ›
Chain: T
Length: 75 amino acids
Theoretical weight: 8.72 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P13726 (Residues: 38-112; Coverage: 29%)
Gene name: F3
Structure domains: Immunoglobulins
Tissue factor Chain: U
Molecule details ›
Chain: U
Length: 116 amino acids
Theoretical weight: 13.35 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P13726 (Residues: 123-242; Coverage: 44%)
Gene name: F3
Structure domains: Immunoglobulins

Ligands and Environments


1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS
Spacegroup: P212121
Unit cell:
a: 70.993Å b: 81.302Å c: 125.86Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 not available
Expression system: Not provided