X-ray diffraction
1.8Å resolution

Crystal Structure of the Auto-Inhibited Kinase Domain of Calcium/Calmodulin Activated Kinase II


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Calcium/calmodulin-dependent protein kinase type II Chains: A, B
Molecule details ›
Chains: A, B
Length: 362 amino acids
Theoretical weight: 40.63 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli BL21(DE3)
  • Canonical: O62305 (Residues: 1-309; Coverage: 43%)
  • Best match: O62305-9 (Residues: 1-343)
Gene names: K11E8.1, unc-43
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P21
Unit cell:
a: 46.121Å b: 77.104Å c: 119.52Å
α: 90° β: 96.74° γ: 90°
R R work R free
0.216 0.216 0.236
Expression system: Escherichia coli BL21(DE3)