X-ray diffraction
2.1Å resolution

X-ray crystal structure of Protein Phosphatase-1 with the marine toxin motuporin bound


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Chain: A
Molecule details ›
Chain: A
Length: 323 amino acids
Theoretical weight: 37.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P36873 (Residues: 1-323; Coverage: 100%)
Gene name: PPP1CC
Sequence domains:
Structure domains: Purple Acid Phosphatase; chain A, domain 2
Molecule details ›
Chain: B
Length: 5 amino acids
Theoretical weight: 786 Da
Source organism: Theonella sp.
Expression system: Not provided

Ligands and Environments

2 bound ligands:
3 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P42212
Unit cell:
a: 100.955Å b: 100.955Å c: 63.485Å
α: 90° β: 90° γ: 90°
R R work R free
0.223 0.221 0.264
Expression systems:
  • Escherichia coli
  • Not provided