PDBe 2b90

X-ray diffraction
2.1Å resolution

Crystal structure of the interleukin-4 variant T13DR85A


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Interleukin-4 Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P05112 (Residues: 25-153; Coverage: 100%)
Gene name: IL4
Sequence domains: Interleukin 4
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P41212
Unit cell:
a: 91.33Å b: 91.33Å c: 45.78Å
α: 90° β: 90° γ: 90°
R R work R free
0.216 0.214 0.249
Expression system: Escherichia coli