Solution NMR

Structure of ADAR2 dsRBM1


Function and Biology Details

Reaction catalysed:
Adenine in double-stranded RNA + H(2)O = hypoxanthine in double-stranded RNA + NH(3)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Double-stranded RNA-specific editase 1 Chain: A
Molecule details ›
Chain: A
Length: 73 amino acids
Theoretical weight: 7.92 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P51400 (Residues: 74-146; Coverage: 10%)
Gene names: Adarb1, Red1
Sequence domains: Double-stranded RNA binding motif
Structure domains: Double Stranded RNA Binding Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)