› 2b1o

Solution NMR

Solution Structure of Ca2+-bound DdCAD-1

Released:
DOI: 10.2210/pdb2b1o/pdb
PDB entry 2b1o coloured by chain, ensemble of 10 models, front view.
PDB entry 2b1o coloured by chain, ensemble of 10 models, side view.
PDB entry 2b1o coloured by chain, ensemble of 10 models, top view.
Source organism: Dictyostelium discoideum
Primary publication:
Solution structures of the adhesion molecule DdCAD-1 reveal new insights into Ca(2+)-dependent cell-cell adhesion.
Lin Z, Sriskanthadevan S, Huang H, Siu CH, Yang D
Nat Struct Mol Biol 13 1016-22 (2006)
PMID: 17057715

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157074 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-dependent cell adhesion molecule 1 Chain: A
Molecule details ›
Chain: A
Length: 212 amino acids
Theoretical weight: 23.82 KDa
Source organism: Dictyostelium discoideum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P54657 (Residues: 2-213; Coverage: 100%)
Gene names: DDB_G0285793, cad1, cadA
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CA 3 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

Molecular evolution of the cadherin superfamily.
Hulpiau et al. (2009)
7 more

1 mention without citation

The FEATURE framework for protein function annotation: modeling new functions, improving performance, and extending to novel applications.
Halperin et al. (2008)