› 2axh

X-ray diffraction
2.7Å resolution

Crystal structures of T cell receptor beta chains related to rheumatoid arthritis

Released:
DOI: 10.2210/pdb2axh/pdb
PDB entry 2axh coloured by chain, front view.
PDB entry 2axh coloured by chain, side view.
PDB entry 2axh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.
Li H, Van Vranken S, Zhao Y, Li Z, Guo Y, Eisele L, Li Y
Protein Sci 14 3025-38 (2005)
PMID: 16260763

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo dodecamer
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-134785 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T cell receptor beta constant 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 242 amino acids
Theoretical weight: 27.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01850 (Residues: 1-129; Coverage: 73%)
Gene name: TRBC1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P6322
Unit cell:
a: 187.334Å b: 187.334Å c: 86.279Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.237 0.237 0.28
Expression system: Escherichia coli

Quick links

Citations

5 citation in other articles

Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC.
Wang et al. (2007)
4 more

1 mention without citation

Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.
Li et al. (2005)