PDBe 2arf

Solution NMR

Solution structure of the Wilson ATPase N-domain in the presence of ATP

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
WND/140 kDa Chain: A
Molecule details ›
Chain: A
Length: 165 amino acids
Theoretical weight: 17.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P35670 (Residues: 1032-1196; Coverage: 11%)
Gene names: ATP7B, PWD, WC1, WND
Structure domains: Calcium-transporting ATPase, cytoplasmic domain N

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: torsion angle dynamics, simulated annealing
Chemical shifts: BMR6914  
Expression system: Escherichia coli BL21