2adc

Solution NMR

Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Polypyrimidine tract-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 229 amino acids
Theoretical weight: 25.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P26599 (Residues: 324-531; Coverage: 39%)
Gene names: PTB, PTBP1
Sequence domains: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Structure domains: Alpha-Beta Plaits
5'-R(*CP*UP*CP*UP*CP*U)-3' Chains: B, C
Molecule details ›
Chains: B, C
Length: 6 nucleotides
Theoretical weight: 1.79 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided