2a72

X-ray diffraction
2Å resolution

Structure of the regulator of G-protein signaling domain of RGS7

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulator of G-protein signaling 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 146 amino acids
Theoretical weight: 17.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49802 (Residues: 320-463; Coverage: 29%)
Gene name: RGS7
Sequence domains: Regulator of G protein signaling domain
Structure domains: Regulator of G-protein Signalling 4, domain 2

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E DW
Spacegroup: P21
Unit cell:
a: 28.915Å b: 106.033Å c: 52.49Å
α: 90° β: 103.71° γ: 90°
R-values:
R R work R free
0.188 0.184 0.249
Expression system: Escherichia coli