2a1u

X-ray diffraction
2.11Å resolution

Crystal structure of the human ETF E165betaA mutant

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Electron transfer flavoprotein subunit alpha, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 333 amino acids
Theoretical weight: 35.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13804 (Residues: 1-333; Coverage: 100%)
Gene name: ETFA
Sequence domains:
Structure domains:
Electron transfer flavoprotein subunit beta Chain: B
Molecule details ›
Chain: B
Length: 255 amino acids
Theoretical weight: 27.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P38117 (Residues: 1-255; Coverage: 100%)
Gene names: ETFB, FP585
Sequence domains: Electron transfer flavoprotein domain
Structure domains: HUPs

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 47.086Å b: 62.869Å c: 174.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.179 0.247
Expression system: Escherichia coli