X-ray diffraction
2.7Å resolution

Crystal structure of human Glycyl-tRNA synthetase (GlyRS) in complex with Glycine and ATP

Source organism: Homo sapiens
Entry authors: Guo RT, Yang XL, Schimmel P

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glycine--tRNA ligase Chain: A
Molecule details ›
Chain: A
Length: 693 amino acids
Theoretical weight: 78.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P41250 (Residues: 55-739; Coverage: 93%)
Gene names: GARS, GARS1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: C2221
Unit cell:
a: 116.526Å b: 139.748Å c: 132.404Å
α: 90° β: 90° γ: 90°
R R work R free
0.238 0.238 0.269
Expression system: Escherichia coli