2zne

X-ray diffraction
2.2Å resolution

Crystal structure of Zn2+-bound form of des3-23ALG-2 complexed with Alix ABS peptide

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
Non-polymer only dimer (preferred)
Non-polymer only tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Programmed cell death protein 6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 169 amino acids
Theoretical weight: 19.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75340 (Residues: 24-191; Coverage: 88%)
Gene names: ALG2, PDCD6
Sequence domains:
Structure domains: EF-hand
Programmed cell death 6-interacting protein Chains: C, D
Molecule details ›
Chains: C, D
Length: 16 amino acids
Theoretical weight: 1.77 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q8WUM4 (Residues: 799-814; Coverage: 2%)
Gene names: AIP1, ALIX, KIAA1375, PDCD6IP

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: C2221
Unit cell:
a: 47.449Å b: 88.509Å c: 211.556Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.223 0.274
Expression systems:
  • Escherichia coli
  • Not provided