PDBe 2yme

X-ray diffraction
2.4Å resolution

Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with granisetron


Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Soluble acetylcholine receptor Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 205 amino acids
Theoretical weight: 23.34 KDa
Source organism: Aplysia californica
Expression system: Spodoptera frugiperda
  • Canonical: Q8WSF8 (Residues: 20-224; Coverage: 95%)
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 83.09Å b: 138.9Å c: 119.89Å
α: 90° β: 91.07° γ: 90°
R R work R free
0.172 0.17 0.226
Expression system: Spodoptera frugiperda