2ykg

X-ray diffraction
2.5Å resolution

Structural insights into RNA recognition by RIG-I

Released:
Source organism: Homo sapiens
Primary publication:
Structural insights into RNA recognition by RIG-I.
Cell 147 409-22 (2011)
PMID: 22000018

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Antiviral innate immune response receptor RIG-I Chain: A
5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3' Chains: C, D
Molecule details ›
Chains: C, D
Length: 10 nucleotides
Theoretical weight: 3.21 KDa
Source organism: Homo sapiens

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P212121
Unit cell:
a: 47.618Å b: 76.208Å c: 219.825Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.22 0.273