PDBe 2xz5

X-ray diffraction
2.8Å resolution

MMTS-modified Y53C mutant of Aplysia AChBP in complex with acetylcholine

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Soluble acetylcholine receptor Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 217 amino acids
Theoretical weight: 24.67 KDa
Source organism: Aplysia californica
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8WSF8 (Residues: 20-236; Coverage: 100%)
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain

Ligands and Environments


1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: C2221
Unit cell:
a: 82.123Å b: 119.405Å c: 267.744Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.175 0.173 0.219
Expression system: Spodoptera frugiperda