2xsz

X-ray diffraction
3Å resolution

The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
RuvB-like 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 367 amino acids
Theoretical weight: 40.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y265 (Residues: 2-456; Coverage: 77%)
Gene names: INO80H, NMP238, RUVBL1, TIP49, TIP49A
Sequence domains:
Structure domains:
RuvB-like 2 Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 378 amino acids
Theoretical weight: 42.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y230 (Residues: 2-463; Coverage: 78%)
Gene names: CGI-46, INO80J, RUVBL2, TIP48, TIP49B
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2221
Unit cell:
a: 111.824Å b: 187.925Å c: 244.889Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.178 0.205
Expression system: Escherichia coli BL21(DE3)