› › Structure analysis

CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMAN PIK3R2

X-ray diffraction
2.09Å resolution
PDB entry 2xs6 coloured by chain, front view.
PDB entry 2xs6 coloured by chain, side view.
PDB entry 2xs6 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Phosphatidylinositol 3-kinase regulatory subunit beta
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 15820.42 Å2
Buried surface area: 1632.6 Å2
Dissociation area: 670.71 Å2
Dissociation energy (ΔGdiss): -1 kcal/mol
Dissociation entropy (TΔSdiss): 11.95 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-126296

Macromolecules

Phosphatidylinositol 3-kinase regulatory subunit beta
Chain: A
Length: 214 amino acids
Theoretical weight: 22.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00459 (Residues: 108-298; Coverage: 26%)
Gene name: PIK3R2
Pfam: RhoGAP domain
InterPro:
CATH: Rho GTPase activation protein
Phosphatidylinositol 3-kinase regulatory subunit beta in PDB entry 2xs6, assembly 1, front view.
Phosphatidylinositol 3-kinase regulatory subunit beta in PDB entry 2xs6, assembly 1, side view.
Phosphatidylinositol 3-kinase regulatory subunit beta in PDB entry 2xs6, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links