PDBe 2xny

X-ray diffraction
7.5Å resolution

A fragment of streptococcal M1 protein in complex with human fibrinogen

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero trimer (preferred)
homo dimer
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Fibrinogen alpha chain Chains: A, D
Molecule details ›
Chains: A, D
Length: 87 amino acids
Theoretical weight: 10.24 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02671 (Residues: 130-216; Coverage: 10%)
Gene name: FGA
Fibrinogen beta chain Chains: B, E
Molecule details ›
Chains: B, E
Length: 328 amino acids
Theoretical weight: 37.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02675 (Residues: 164-491; Coverage: 71%)
Gene name: FGB
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain
Fibrinogen gamma chain Chains: C, F
Molecule details ›
Chains: C, F
Length: 319 amino acids
Theoretical weight: 36.22 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02679 (Residues: 114-432; Coverage: 75%)
Gene names: FGG, PRO2061
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain
M PROTEIN Chains: M, N
Molecule details ›
Chains: M, N
Length: 102 amino acids
Theoretical weight: 12.07 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli BL21

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P3221
Unit cell:
a: 165.687Å b: 165.687Å c: 289.652Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.423 0.424 0.408
Expression system: Escherichia coli BL21