2xn4

X-ray diffraction
1.99Å resolution

Crystal structure of the kelch domain of human KLHL2 (Mayven)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kelch-like protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 302 amino acids
Theoretical weight: 32.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O95198 (Residues: 294-591; Coverage: 50%)
Gene name: KLHL2
Sequence domains: Kelch motif
Structure domains: Kelch-type beta propeller

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P1
Unit cell:
a: 45.994Å b: 46.005Å c: 71.762Å
α: 86.68° β: 82.75° γ: 68.48°
R-values:
R R work R free
0.172 0.169 0.222
Expression system: Escherichia coli BL21(DE3)