PDBe 2xmc

X-ray diffraction
2.4Å resolution

G117H mutant of human butyrylcholinesterase in complex with fluoride anion

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cholinesterase Chain: A
Molecule details ›
Chain: A
Length: 529 amino acids
Theoretical weight: 59.79 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P06276 (Residues: 29-557; Coverage: 92%)
Gene names: BCHE, CHE1
Sequence domains: Carboxylesterase family

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: I422
Unit cell:
a: 155.59Å b: 155.59Å c: 127.99Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.192 0.252
Expression system: Cricetulus griseus