2x8a

X-ray diffraction
2.6Å resolution

Human Nuclear Valosin containing protein Like (NVL), C-terminal AAA- ATPase domain

Released:
Source organism: Homo sapiens
Entry authors: Moche M, Schuetz P, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson I, Kallas A, Karlberg T, Kotenyova T, Kraulis P, Nordlund P, Nyman T, Persson C, Sehic A, Siponen MI, Svensson L, Thorsell AG, Tresaugues L, VanDenBerg S, Wahlberg E, Weigelt J, Welin M, Wisniewska M, Schuler H

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear valosin-containing protein-like Chain: A
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 29.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O15381 (Residues: 573-845; Coverage: 32%)
Gene names: NVL, NVL2
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P61
Unit cell:
a: 77.989Å b: 77.989Å c: 86.038Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.214 0.21 0.25
Expression system: Escherichia coli BL21(DE3)