PDBe 2x00

X-ray diffraction
2.4Å resolution

CRYSTAL STRUCTURE OF A-ACHBP IN COMPLEX WITH GYMNODIMINE A

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Soluble acetylcholine receptor Chains: A, B, C, E
Molecule details ›
Chains: A, B, C, E
Length: 228 amino acids
Theoretical weight: 25.97 KDa
Source organism: Aplysia californica
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8WSF8 (Residues: 16-236; Coverage: 100%)
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain
Soluble acetylcholine receptor Chain: D
Molecule details ›
Chain: D
Length: 227 amino acids
Theoretical weight: 25.84 KDa
Source organism: Aplysia californica
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8WSF8 (Residues: 18-236; Coverage: 100%)
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 74.43Å b: 124.32Å c: 130.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.18 0.235
Expression system: Homo sapiens