2wnu

X-ray diffraction
2.3Å resolution

Complex between c1q globular heads and heparan sulfate

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Complement C1q subcomponent subunit A Chains: A, D
Molecule details ›
Chains: A, D
Length: 134 amino acids
Theoretical weight: 14.99 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02745 (Residues: 112-245; Coverage: 60%)
Gene name: C1QA
Sequence domains: C1q domain
Structure domains: Jelly Rolls
Complement C1q subcomponent subunit B Chains: B, E
Molecule details ›
Chains: B, E
Length: 136 amino acids
Theoretical weight: 15.4 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02746 (Residues: 118-253; Coverage: 60%)
Gene name: C1QB
Sequence domains: C1q domain
Structure domains: Jelly Rolls
Complement C1q subcomponent subunit C Chains: C, F
Molecule details ›
Chains: C, F
Length: 131 amino acids
Theoretical weight: 14.56 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02747 (Residues: 115-245; Coverage: 60%)
Gene names: C1QC, C1QG
Sequence domains: C1q domain
Structure domains: Jelly Rolls

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P1
Unit cell:
a: 48.09Å b: 48.16Å c: 87.73Å
α: 92.86° β: 92.2° γ: 113.64°
R-values:
R R work R free
0.201 0.198 0.256