PDBe 2wmd

X-ray diffraction
2Å resolution

Crystal structure of NmrA-like family domain containing protein 1 in complex with NADP and 2-(4-chloro-phenylamino)-nicotinic acid

Released:
Source organism: Homo sapiens
Entry authors: Bhatia C, Pilka E, Niesen F, Yue WW, Ugochukwu E, Savitsky P, Hozjan V, Roos AK, Filippakopoulos P, von Delft F, Heightman T, Arrowsmith C, Weigelt J, Edwards A, Bountra C, Oppermann U

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NmrA-like family domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 299 amino acids
Theoretical weight: 33.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Best match: Q9HBL8 (Residues: 1-298)
Gene names: HSCARG, NMRAL1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Unit cell:
a: 57.722Å b: 79.734Å c: 86.362Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.202 0.248
Expression system: Escherichia coli BL21(DE3)