Function and Biology Details
Reaction catalysed:
ATP + H(2)O + 4 H(+)(Side 1) = ADP + phosphate + 4 H(+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- P-loop containing nucleoside triphosphate hydrolase
- ATP synthase, F1 complex, alpha subunit
- ATP synthase, F1 complex, gamma subunit
- ATP synthase, F1 complex, beta subunit
- ATP synthase, alpha subunit, C-terminal
- ATPase, alpha/beta subunit, nucleotide-binding domain, active site
- ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
- ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain
14 more domains
Structure analysis Details
Assembly composition:
hetero nonamer (preferred)
Assembly name:
ATP synthase F(1) complex mitochondrial (preferred)
PDBe Complex ID:
PDB-CPX-133621 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
ATP synthase F(1) complex subunit alpha, mitochondrial
Molecule details ›
Chains: A, B, C
Length: 553 amino acids
Theoretical weight: 59.8 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Length: 553 amino acids
Theoretical weight: 59.8 KDa
Source organism: Bos taurus
UniProt:
- Canonical:
P19483 (Residues: 1-553; Coverage: 100%)
Sequence domains:
- ATP synthase alpha/beta family, beta-barrel domain
- ATP synthase alpha/beta family, nucleotide-binding domain
- ATP synthase alpha/beta chain, C terminal domain
ATP synthase F(1) complex catalytic subunit beta, mitochondrial
Molecule details ›
Chains: D, E, F
Length: 528 amino acids
Theoretical weight: 56.34 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Length: 528 amino acids
Theoretical weight: 56.34 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P00829 (Residues: 1-528; Coverage: 100%)
Sequence domains:
- ATP synthase alpha/beta family, beta-barrel domain
- ATP synthase alpha/beta family, nucleotide-binding domain
- C-terminal domain of V and A type ATP synthase
ATP synthase F(1) complex subunit gamma, mitochondrial
Molecule details ›
Chain: G
Length: 298 amino acids
Theoretical weight: 33.12 KDa
Source organism: Bos taurus
UniProt:
Sequence domains: ATP synthase
Structure domains:
Length: 298 amino acids
Theoretical weight: 33.12 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P05631 (Residues: 1-298; Coverage: 100%)
Sequence domains: ATP synthase
Structure domains:
ATP synthase F(1) complex subunit delta, mitochondrial
Molecule details ›
Chain: H
Length: 168 amino acids
Theoretical weight: 17.63 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Length: 168 amino acids
Theoretical weight: 17.63 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P05630 (Residues: 1-168; Coverage: 100%)
Sequence domains:
- ATP synthase, Delta/Epsilon chain, beta-sandwich domain
- Metazoan delta subunit of F1F0-ATP synthase, C-terminal domain
ATP synthase F(1) complex subunit epsilon, mitochondrial
Molecule details ›
Chain: I
Length: 51 amino acids
Theoretical weight: 5.79 KDa
Source organism: Bos taurus
UniProt:
Sequence domains: Mitochondrial ATP synthase epsilon chain
Length: 51 amino acids
Theoretical weight: 5.79 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P05632 (Residues: 1-51; Coverage: 100%)
Sequence domains: Mitochondrial ATP synthase epsilon chain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-2
Spacegroup:
P212121
