› 2vrd

Solution NMR

THE STRUCTURE OF THE ZINC FINGER FROM THE HUMAN SPLICEOSOMAL PROTEIN U1C

Released:
DOI: 10.2210/pdb2vrd/pdb
PDB entry 2vrd coloured by chain, ensemble of 47 models, front view.
PDB entry 2vrd coloured by chain, ensemble of 47 models, side view.
PDB entry 2vrd coloured by chain, ensemble of 47 models, top view.
Source organism: Homo sapiens
Primary publication:
The structure and biochemical properties of the human spliceosomal protein U1C.
Muto Y, Pomeranz Krummel D, Oubridge C, Hernandez H, Robinson CV, Neuhaus D, Nagai K
J Mol Biol 341 185-98 (2004)
PMID: 15312772

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140602 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
U1 small nuclear ribonucleoprotein C Chain: A
Molecule details ›
Chain: A
Length: 61 amino acids
Theoretical weight: 7.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09234 (Residues: 1-61; Coverage: 38%)
Gene name: SNRPC
Sequence domains: U1 zinc finger
Structure domains: Classic Zinc Finger

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Cryo-electron microscopy of spliceosomal components.
Stark et al. (2006)
3 more

3 mentions without citation

Structure-function analysis of the Yhc1 subunit of yeast U1 snRNP and genetic interactions of Yhc1 with Mud2, Nam8, Mud1, Tgs1, U1 snRNA, SmD3 and Prp28.
Schwer et al. (2014)
2 more