2vog

X-ray diffraction
1.9Å resolution

Structure of mouse A1 bound to the Bmf BH3-domain

Released:
Source organism: Mus musculus

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bcl-2-related protein A1 Chain: A
Molecule details ›
Chain: A
Length: 157 amino acids
Theoretical weight: 17.92 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q07440 (Residues: 1-152; Coverage: 88%)
Gene names: A1, Bcl2a1, Bcl2a1a, Bfl1
Sequence domains: Apoptosis regulator proteins, Bcl-2 family
Structure domains: Blc2-like
Bcl-2-modifying factor Chain: B
Molecule details ›
Chain: B
Length: 27 amino acids
Theoretical weight: 3.28 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q91ZE9 (Residues: 126-152; Coverage: 15%)
Gene name: Bmf

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P21212
Unit cell:
a: 66.654Å b: 68.05Å c: 32.136Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.191 0.231
Expression system: Escherichia coli BL21(DE3)