2vj2

X-ray diffraction
2.5Å resolution

Human Jagged-1, domains DSL and EGFs1-3

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein jagged-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 169 amino acids
Theoretical weight: 18.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P78504 (Residues: 185-335; Coverage: 13%)
Gene names: JAG1, JAGL1
Sequence domains: EGF-like domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: C2
Unit cell:
a: 61Å b: 102.3Å c: 62.7Å
α: 90° β: 114.3° γ: 90°
R-values:
R R work R free
0.221 0.22 0.239
Expression system: Escherichia coli