X-ray diffraction
1.1Å resolution

Mouse Profilin IIa in complex with a double repeat from the FH1 domain of mDia1


Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Profilin-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 140 amino acids
Theoretical weight: 15.06 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: Q9JJV2 (Residues: 1-140; Coverage: 100%)
Gene name: Pfn2
Sequence domains: Profilin
Structure domains: Dynein light chain 2a, cytoplasmic
Protein diaphanous homolog 1 Chain: C
Molecule details ›
Chain: C
Length: 21 amino acids
Theoretical weight: 2.01 KDa
Source organism: Mus musculus
Expression system: Not provided
  • Canonical: O08808 (Residues: 635-655; Coverage: 2%)
Gene names: Diap1, Diaph1

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P21
Unit cell:
a: 38.38Å b: 37.27Å c: 88.75Å
α: 90° β: 98.58° γ: 90°
R R work R free
0.146 not available 0.173
Expression systems:
  • Escherichia coli
  • Not provided