2v1x

X-ray diffraction
2Å resolution

Crystal structure of human RECQ-like DNA helicase

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent DNA helicase Q1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 591 amino acids
Theoretical weight: 67.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P46063 (Residues: 49-616; Coverage: 88%)
Gene names: RECQ1, RECQL, RECQL1
Sequence domains:
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 83.229Å b: 97.647Å c: 85.849Å
α: 90° β: 104.5° γ: 90°
R-values:
R R work R free
0.235 0.232 0.278
Expression system: Escherichia coli BL21(DE3)