PDBe 2uzq

X-ray diffraction
2.38Å resolution

Protein Phosphatase, New Crystal Form

Released:
Source organism: Homo sapiens
Entry authors: Hillig RC, Eberspaecher U

Function and Biology Details

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
M-phase inducer phosphatase 2 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 203 amino acids
Theoretical weight: 23.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P30305 (Residues: 391-580; Coverage: 33%)
Gene names: CDC25B, CDC25HU2
Sequence domains: Rhodanese-like domain
Structure domains: Rhodanese-like domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P61
Unit cell:
a: 123.925Å b: 123.925Å c: 174.035Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 0.226 0.249
Expression system: Escherichia coli