PDBe 2uv6

X-ray diffraction
2Å resolution

Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP

Released:

Function and Biology Details

Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5'-AMP-activated protein kinase subunit gamma-1 Chain: A
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 17.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P54619 (Residues: 182-325; Coverage: 44%)
Gene name: PRKAG1
Sequence domains: CBS domain
Structure domains: CBS-domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 66.092Å b: 43.775Å c: 55.786Å
α: 90° β: 119.04° γ: 90°
R-values:
R R work R free
0.176 0.172 0.247
Expression system: Escherichia coli BL21(DE3)