2rr3

Solution NMR

Solution structure of the complex between human VAP-A MSP domain and human OSBP FFAT motif

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vesicle-associated membrane protein-associated protein A Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 14.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9P0L0 (Residues: 11-135; Coverage: 50%)
Gene names: VAP33, VAPA
Sequence domains: MSP (Major sperm protein) domain
Structure domains: Immunoglobulins
Oxysterol-binding protein 1 Chain: B
Molecule details ›
Chain: B
Length: 47 amino acids
Theoretical weight: 5.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P22059 (Residues: 346-379; Coverage: 4%)
Gene names: OSBP, OSBP1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Escherichia coli