2rmj

Solution NMR

Solution structure of RIG-I C-terminal domain

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antiviral innate immune response receptor RIG-I Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95786 (Residues: 792-925; Coverage: 15%)
Gene name: DDX58
Sequence domains: C-terminal domain of RIG-I
Structure domains: RIG-I-like receptor, C-terminal regulatory domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, distance geometry, simulated annealing
Expression system: Escherichia coli