PDBe 2rjk

X-ray diffraction
2.3Å resolution

Crystal Structure of Human TL1A Extracellular Domain C95S Mutant

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor ligand superfamily member 15, secreted form Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 20.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95150 (Residues: 72-251; Coverage: 72%)
Gene names: TL1, TNFSF15, VEGI
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P4132
Unit cell:
a: 118.226Å b: 118.226Å c: 118.226Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.212 0.265
Expression system: Escherichia coli